{Reference Type}: Journal Article

{Author}: Natalia Nowacka；Renata Nowak；Marta Drozd；Marta Olech；Renata Los；Anna Malm

{Year}: 2014

{Title}:Analysis of phenolic constituents, antiradical and antimicrobial activity of edible mushrooms growing wild in Poland

{Tag}: 0

{Star}: 0

{Volume}: 59

{Issue}: 2

{Pages}: 689-694

{DOL}: http://dx.doi.org/10.1016/j.lwt.2014.05.041

{ISBN/ISSN}:0023-6438

{Keywords}: Fungi；Antioxidant；Antibacterial；Phenolic acids；LC-MS

{Abstract}:

         Mushrooms have been part of human diet for centuries. They possess great potential for both nutrition and therapeutic use. Amongst bioactive constituents occurring in mushrooms, phenolic compounds focus much attention due to their antioxidant activity.

         The aim of the present study was to determine the chemical composition of phenolic compounds in wild growing edible mushrooms traditionally eaten in Poland. For this purpose, LC-ESI-MS/MS and spectrophotometric tests were used. Our findings revealed the presence of benzoic acid (protocatechuic, 4-OH-benzoic, vanillic, salicylic) and cinnamic acid derivatives (caffeic, p-coumaric, ferulic) in mushroom extracts. The total phenolic content in different species ranged between 1.64 and 13.53  mg GAE/g of extract. Moreover, antiradical and antimicrobial potential of 19 Polish wild growing edible mushrooms was investigated. As a result, differentiated antiradical activity was disclosed (IC50 from 12.39 to 108.38  mg/mg DPPH). Moderate antimicrobial properties were found, as well.

         To the best of our knowledge, this is the first study conducted among such a large number of wild edible mushroom species. The results obtained indicate that mushrooms might be used directly in diet and promote health as an easily accessible source of natural antioxidants and antimicrobial agents.

{Author Address}:   http://www.sciencedirect.com

{Language}: English

{Reference Type}: Journal Article

{Author}: Zhao-Lin Cai；Chun-Yang Wang；Zhong-Jiao Jiang；Hai-Hang Li；Wen-Xiao Liu；Liang-Wei Gong；Peng Xiao；Chu-Hua Li

{Year}: 2013

{Title}:Effects of cordycepin on Y-maze learning task in mice

{Tag}: 0

{Star}: 0

{Volume}: 714

{Issue}: 1-3

{Pages}: 249-253

{DOL}: http://dx.doi.org/10.1016/j.ejphar.2013.05.049

{ISBN/ISSN}:0014-2999

{Keywords}: Cordycepin；Y-maze test；Healthy；Ischemia；Neuronal loss；Hippocampus

{Abstract}: Cordycepin (3′-deoxyadenosine) is the major bioactive component of Cordyceps militaris that has been widely used in oriental countries as a Traditional Chinese Medicine and healthy food for preventing early aging, improving physical performance and increasing lifespan. Cordyceps militaris extracts other than cordycepin have been reported to improve cognitive function. Although cordycepin is one of the most utilized Cordyceps militaris components, it remains unknown whether cordycepin could improve learning and memory. Here we investigated effects of cordycepin on learning and memory in healthy and ischemic mice using Y-maze test. We found that oral cordycepin administration at dose of 10 mg/kg significantly improved Y-maze learning performance both in healthy and ischemic mice. However, cordycepin at dose of 5 mg/kg enhanced Y-maze learning only in ischemic mice but not healthy mice. In this study, simultaneously, we found that orally administrated cordycepin significantly decreased the neuronal loss induced by ischemia in hippocampal CA1 and CA3 regions. Collectively, our results can provide valuable evidence that cordycepin may act as a nootropic product or potential clinical application in improving cognitive function of patients with ischemic stroke in the future.

{Author Address}:   http://www.sciencedirect.com

{Language}: English

{Reference Type}: Journal Article

{Author}: Zhen-Yuan Zhu；Wei Pang；Yuan-Yuan Li；Xiao-Ran Ge；Li-Jing Chen；Xiao-Cui Liu；Qiang Lv；Guo-Ling Dong；An-Jun Liu；Yongmin Zhang

{Year}: 2014

{Title}:Effect of ultrasonic treatment on structure and antitumor activity of mycelial polysaccharides from Cordyceps gunnii

{Tag}: 0

{Star}: 0

{Volume}: 114

{Issue}: 0

{Pages}: 12-20

{DOL}: http://dx.doi.org/10.1016/j.carbpol.2014.07.068

{ISBN/ISSN}:0144-8617

{Keywords}: C. Gunnii；Mycelial polysaccharide；Ultrasonic, Antitumor activity；Structure

{Abstract}: Taking mycelial polysaccharides from Cordyceps gunnii (C. gunnii) as the study subject, the effect of ultrasonic power, time and concentration of polysaccharides on antitumor activity of the polysaccharides was investigated. The ultrasonic processing condition of the polysaccharides was optimized by using orthogonal test design, and determined to be 400 W, 15 min and 1 g/L. The change of structures of polysaccharides before and after ultrasonic treatment was also studied. Results show that ultrasonic treatment did not change the characteristic attribute of polysaccharides from C. gunnii. The composition of monosaccharide residues and the category of glycosidic bond have not been changed. But the molecular weight and intrinsic viscosity was reduced, and the alpha-helicity was enhanced after ultrasonic treatment. It was possible that ultrasonic treatment is an effective way for enhancing antitumor activity of polysaccharides.

{Author Address}:   http://www.sciencedirect.com

{Language}: English